ACTIGERMINA BACILLUS CLAUSII SPORES 5ML 10S

Overview & Mechanism of Action

• Actigermina (5ml x 10 mini-vials) is a targeted oral probiotic solution designed to restore the physiological balance of gut microflora in both children and adults:
• Gastric Acid Resilience & Intestinal Germination: Bacillus clausii spores feature a protective coat that enables them to pass through acidic stomach juices unharmed. Upon reaching the intestine, spores germinate into active vegetative cells that multiply rapidly to rebuild beneficial microflora (eubiosis).
• Pathogen Inhibition & Mucosal Protection: Competes with pathogenic organisms for adhesion sites on the intestinal mucosa, secretes bacteriocins, and promotes barrier function to prevent bacterial translocation and shorten diarrhea duration.
• Immune Modulation & Vitamin Synthesis: Stimulates localized secretory immunoglobulin A (sIgA) release to strengthen gut mucosal immunity, while actively synthesizing B-complex vitamins to restore nutrient depletion caused by dysbiosis.
• Polyantibiotic Resistance: Resistant to a wide range of common antibiotic agents (such as penicillins, cephalosporins, and macrolides), enabling effective co-administration during antibiotic treatment to protect gut microbiota from disruption.

Clinical Indications

• Actigermina Bacillus Clausii Spores 5ml 10s is indicated for:
• Treatment and prevention of gut dysbiosis (microbial imbalance) and endogenous vitamin deficiencies
• Symptomatic management of acute and chronic diarrhea due to gastrointestinal infections or food changes
• Prevention and adjuvant treatment of Antibiotic-Associated Diarrhea (AAD) in pediatric and adult patients
• Restoring healthy intestinal flora in infants and young children experiencing digestive disturbances

Usage Guidance & Safety Precautions

Administration:

• For oral use only. Break off the top of the single-dose mini-vial and swallow the solution directly or dilute in water, milk, or fruit juice. Consume immediately after opening.

Recommended Dosage:

• Adults: 2 to 3 mini-vials (5ml each) per day at regular intervals.
• Infants & Children (over 3 weeks): 1 to 2 mini-vials (5ml each) per day.
• During Antibiotic Therapy: Administer Actigermina in the interval between antibiotic doses.

Precautions & Warnings:

• FOR ORAL USE ONLY. DO NOT INJECT OR ADMINISTER PARENTERALLY. If severe diarrhea persists beyond 2–3 days or signs of dehydration appear, consult a healthcare provider promptly. Store below 30°C in a cool, dry place protected from direct heat and light. Keep out of reach of children.