ASPASWEET TABLETS 450S

Overview & Mechanism of Action

• Aspasweet Tablets (dispenser pack of 450 micro-tablets) provides a convenient, fast-dissolving non-nutritive sweetener designed to substitute refined sugar without elevating blood glucose
• High-Intensity Sweetening Action: Delivers intense sweetness (~200 times sweeter than sucrose/table sugar) per tablet. Because only a minute quantity is required to achieve the sweetening equivalence of 1 teaspoon of sugar ($4\text{ g}$ sucrose), its caloric contribution per serving is virtually zero ($<1\text{ kcal}$).
• Glycemic & Insulin Neutrality: Unlike refined carbohydrates and simple sugars, non-nutritive intense sweeteners do not stimulate insulin secretion from pancreatic beta cells nor cause postprandial blood glucose spikes, making them an effective substitute for glycemic management.
• Non-Cariogenic Dental Protection: Oral bacteria (e.g., Streptococcus mutans) cannot ferment aspartame into organic acids, thereby preventing tooth enamel demineralization and reducing the risk of dental caries.

Clinical Indications

• Aspasweet Tablets 450s is indicated for:
• Replacement of refined table sugar in hot beverages (tea, coffee, cocoa) and cold drinks
• Dietary management for individuals with Type 1 Diabetes, Type 2 Diabetes, or Gestational Diabetes seeking strict glycemic control
• Weight loss, weight maintenance, and calorie-controlled nutritional regimens
• Reducing overall dietary sugar intake to support dental health

Usage Guidance & Safety Precautions

Administration:

• Drop 1 or more tablets into hot or cold beverages and stir briefly until completely dissolved. 1 tablet provides sweetness equivalent to approximately 1 teaspoon of table sugar.

Recommended Dosage:

• Use as desired to replace table sugar. Stay within the Acceptable Daily Intake (ADI) established for aspartame ($40\text{--}50\text{ mg/kg}$ body weight/day).

Precautions & Warnings:

• Contraindicated in individuals with Phenylketonuria (PKU), as aspartame metabolizes into phenylalanine. Not intended for prolonged baking at high temperatures, as intense heat can cause sweetening compounds to break down and lose sweetness. Store below 25°C in a dry place with the dispenser cap securely closed. Keep out of reach of children.