CARTIMOVE D TABS 10S

Overview & Mechanism of Action

• Cartimove D Tablets (strip of 10 tablets) provides targeted therapeutic action designed to slow the structural progression of osteoarthritis and maintain articular function:
• Targeted Anti-Cytokine Action (Diacerein): Directly inhibits Interleukin-1 beta, a primary pro-inflammatory cytokine involved in cartilage destruction and synovial inflammation. Downregulates matrix metalloproteinases (MMPs) and lysosomal enzymes, preventing cartilage matrix breakdown and chondrocyte apoptosis.
• Cartilage Matrix Biosynthesis (Glucosamine Sulfate/HCl): Functions as an essential biochemical precursor for glycosaminoglycans (GAGs), proteoglycans, and hyaluronic acid in the extracellular cartilage matrix and synovial fluid.
• Synergistic Joint Protection & Lubrication: Enhances synovial fluid viscosity, reduces mechanical friction across weight-bearing joints, and promotes repair of micro-damaged articular surfaces over time.

Clinical Indications

• Cartimove D Tablets 10s is indicated for:
• Management and symptomatic relief of mild-to-moderate osteoarthritis of the knee, hip, and spine
• Slowing the structural progression of joint space narrowing and cartilage loss
• Relief of chronic joint stiffness, swelling, and movement-induced arthritic pain

Usage Guidance & Safety Precautions

Administration:

• Take orally with meals to minimize gastrointestinal discomfort. Swallow the tablet whole with a glass of water.

Recommended Dosage:

• Adults: 1 tablet once or twice daily, or as directed by an orthopedic physician. Clinical benefits typically manifest after 2 to 4 weeks of consistent administration.

Precautions & Warnings:

• Diacerein may cause initial mild laxative effects or soft stools during the first few weeks of therapy; monitor fluid balance. May cause a harmless, reversible yellow/orange discoloration of urine. Contraindicated in patients with severe hepatic impairment, inflammatory bowel disease, or intestinal obstruction. Exercise caution in individuals with known shellfish allergies if glucosamine is marine-derived. Store below 25°C in a dry place away from direct sunlight. Keep out of reach of children.