HARMOFINE INSULIN PEN NEEDLES 33G*4MM 100S

Overview & Mechanism of Action

• Harmofine Insulin Pen Needles ($33\text{G} \times 4\text{mm}$, 100 sterile needles per box) provide reliable, low-pain subcutaneous drug administration:
• Ultra-Fine 33G Needle Geometry: Features an outer diameter of approximately $0.20\text{mm}$ with a precision electro-polished tri-bevel tip. This significantly decreases insertion resistance and skin trauma, ensuring a virtually painless injection experience.
• 4mm Short Length & Intramuscular Risk Reduction: The $4\text{mm}$ needle length reliably targets the subcutaneous fat layer across all body types (BMI ranges) without penetrating underlying muscle tissue, eliminating the need for skin folding in most patients and preventing accidental intramuscular injection.
• Extra-Thin Wall (ETW) Technology & Universal Fit: Designed with a widened internal lumen to optimize fluid flow rate and lower thumb-plunger pressure during delivery. Built in accordance with ISO 11608-2 standards to fit all major diabetes injection pens (e.g., NovoPen, SoloStar, KwikPen, FlexTouch, Humapen).

Clinical Indications & Uses

• Harmofine Insulin Pen Needles 33G*4mm 100s are indicated for:
• Daily subcutaneous administration of rapid-acting, short-acting, intermediate-acting, or long-acting basal insulins in adult and pediatric diabetic patients
• Delivery of GLP-1 receptor agonist therapies (e.g., semaglutide, liraglutide, dulaglutide) and subcutaneous human growth hormone (hGH) regimens
• Patients seeking to minimize injection discomfort, local tissue bruising, or lipohypertrophy associated with thicker or longer needles

Usage Guidance & Safety Precautions

Administration:

• Attach a fresh sterile needle tightly onto the injection pen at a $90^\circ$ angle. Perform a 1-to-2 unit air shot (priming) to ensure drug flow. Inject perpendicularly into clean skin (abdomen, thighs, or buttocks) without pinching a skin fold (unless advised by a clinician). Depress the plunger fully and hold in place for 6 to 10 seconds before withdrawing to prevent medication leakage.

Recommended Dosage:

• Use a new, single-use needle for every injection to preserve needle lubricity, sterile barrier integrity, and prevent clogging or tissue damage.

Precautions & Warnings:

• For subcutaneous injection only. Reusing pen needles bends the tip, strips the silicone coating, increases lipohypertrophy risk, and introduces microbial contamination. Do not store the pen with the needle attached to avoid air entrainment or drug leakage. Immediately discard used needles into a puncture-resistant medical sharps container. Store unopened boxes below $25^\circ\text{C}$ in a clean, dry place away from heat and moisture. Keep out of reach of children.