OATVEEN ULTRA 20% UREA CREAM 150ML

Overview & Mechanism of Action

• Oatveen Ultra 20% Urea Cream ($150\text{ml}$ pump bottle/dispenser) provides dual-action keratolytic exfoliation and natural moisture-binding restoration for severely compromised, hyperkeratotic skin:
• Keratolytic Protein Deaggregation (20% Urea): At a high concentration of $20\%$, urea disrupts hydrogen bonding in epidermal keratin proteins, loosening cross-linked horny layer cells. This encourages gentle desquamation (shedding) of thickened stratum corneum plaques and rough, bumpy skin without mechanical abrasion.
• Intensive Moisture Retention: Acts as a natural moisturizing factor ($\text{NMF}$) component, drawing water into intercellular matrix spaces within the epidermis to drastically increase cutaneous hydration levels and improve skin elasticity.
• Barrier Soothing & Anti-Itch Protection (Colloidal Oatmeal): Enriched with colloidal oatmeal, which delivers avenanthramides and beta-glucans to soothe localized inflammation, calm pruritus (itching), and establish a protective lipid membrane that prevents transepidermal water loss ($\text{TEWL}$).

Clinical Indications & Uses

• Oatveen Ultra 20% Urea Cream 150ml is indicated for:
• Intensive management of severe dry skin conditions (xerosis, ichthyosis, eczema, and stable psoriatic plaques)
• Softening and smoothing rough, bumpy skin textures such as keratosis pilaris ("strawberry skin")
• Reducing thickened, hardened, or calloused skin areas on heels, elbows, knees, and hands

Usage Guidance & Safety Precautions

Administration:

• Apply to clean, slightly damp skin after bathing. Gently massage into affected areas until fully absorbed.

Recommended Dosage:

• Adults and Children over 3 years: Apply 1 to 2 times daily to target dry, rough, or hyperkeratotic skin areas, or as directed by a dermatologist.

Precautions & Warnings:

• For external dermatological use only. Do not apply to inflamed, broken, weeping skin, or open wounds. Mild, temporary stinging or burning may occur if applied to severely cracked skin or sensitive facial areas. Avoid contact with eyes and mucous membranes; wash hands after application unless treating the hands. Store below $25^\circ\text{C}$ in a cool, dry place away from direct heat. Keep out of reach of children.