Physiogel Calming Relief A.I Body Lotion 100ml

Overview & Mechanism of Action

• Physiogel Calming Relief A.I. Body Lotion ($100\text{ml}$ bottle formulated with Palmitoylethanolamide $\text{PEA}$ and essential physiological lipids) provides targeted cutaneous barrier restoration and neuro-calming activity:
• Endogenous Anti-Itch & Anti-Inflammatory Signaling ($\text{PEA}$ Action): Enriched with Palmitoylethanolamide ($\text{PEA}$), a naturally occurring fatty acid amide that acts on cutaneous nerve endings and mast cells. $\text{PEA}$ inhibits mast cell degranulation and reduces pro-inflammatory signaling pathways, directly alleviating itch sensations and cutaneous erythema.
• BioMimic Lipid Technology: Features a specialized derma-membrane structure that replicates the natural lamellar arrangement of intercellular lipids found in healthy stratum corneum. It supplies essential phospholipids, ceramides, and squalane to rebuild broken lipid barriers.
• Transepidermal Water Loss ($\text{TEWL}$) Suppression: Seals micro-fissures in damaged or dry skin without clogging pores (non-comedogenic), locking in deep hydration and forming a protective shield against external irritants, environmental allergens, and harsh weather.

Clinical Indications & Uses

• Physiogel Calming Relief A.I. Body Lotion 100ml is indicated for:
• Daily emollient care and symptomatic relief of dry, itchy, red, and reactive skin conditions, including eczema and atopic dermatitis
• Restoring a compromised skin barrier following environmental exposure, harsh dermatological treatments, or seasonal xerosis
• Hydrating and soothing hyper-sensitive skin prone to irritation, tightness, and recurring itchiness

Usage Guidance & Safety Precautions

Administration:

• Apply generously to clean skin across the body twice daily or as needed. Massage gently in circular motions until fully absorbed.

Recommended Dosage:

• Adults, Children, and Infants: Apply twice daily (morning and evening), or as frequently as necessary to calm irritated, dry body areas.

Precautions & Warnings:

• For external dermatological use only. Avoid direct contact with eyes; if contact occurs, rinse immediately with clean water. Discontinue use if localized allergic reaction or unexpected irritation occurs. Free from conventional emulsifiers, fragrances, preservatives, and colorants. Store below $25^\circ\text{C}$ in a cool, dry place away from direct heat and light. Keep out of reach of children.