RENOGOLD TABS 30S

Overview & Mechanism of Action

• Renogold Tablets ($30\text{-tablet}$ pack formulated with alpha-ketoanalogues of essential amino acids and renal-targeted amino acid precursors) supports metabolic equilibrium in chronic kidney disease ($\text{CKD}$):
• Transamination & Nitrogenous Waste Reduction: Alpha-ketoacids accept amino groups from non-essential amino acids via hepatic transamination, converting nitrogenous waste into essential L-amino acids. This recycles circulating blood urea nitrogen ($\text{BUN}$) and lowers serum urea without adding exogenously bound nitrogen.
• Protein-Energy Wasting ($\text{PEW}$) Prevention: Delivers essential amino acid building blocks required for muscle protein synthesis and nitrogen balance while allowing patients to adhere to low-protein dietary regimens.
• Mineral & Bone Homeostasis: Reduces hyperphosphatemia and helps manage secondary hyperparathyroidism, helping slow down the progression of renal osteodystrophy.

Clinical Indications & Uses

• Renogold Tablets 30s is indicated for:
• Prevention and therapeutic management of metabolic complications arising from impaired protein metabolism in Chronic Kidney Disease ($\text{CKD}$, Stages 3 to 5)
• Reduction of uremic symptoms (such as fatigue, nausea, and loss of appetite) and delaying the necessity of renal replacement therapy (dialysis) in conjunction with a low-protein diet
• Dietary management of protein catabolism, hyperphosphatemia, and amino acid imbalances in renal failure patients

Usage Guidance & Safety Precautions

Administration:

• Swallow tablets whole during meals. Consuming tablets with food facilitates proper transamination, enhances intestinal absorption, and minimizes gastrointestinal upset.

Recommended Dosage:

• Adults with Chronic Kidney Disease: Take 1 to 2 tablets 3 times daily with meals, or strictly as individually prescribed by a nephrologist based on body weight and biochemical markers ($\text{BUN}$, serum creatinine).

Precautions & Warnings:

• For oral administration under medical supervision. Contraindicated in patients with hypercalcemia, severe hyperkalemia, or inherited amino acid metabolism disorders. Regular laboratory monitoring of serum calcium, phosphate, and renal function is required during treatment. Ensure adequate caloric intake during therapy to prevent muscle catabolism. Store below $25^\circ\text{C}$ in a cool, dry place protected from light and moisture. Keep out of reach of children.