UP 2 HEMA ORAL LIQUID 10ML 10S

Overview & Mechanism of Action

• Up 2 Hema Oral Liquid ($10\text{-vial}$ pack containing $10\text{ml}$ single-dose oral liquid vials) delivers essential hematinic factors required for optimal erythropoiesis and tissue oxygenation:
• Bioavailable Non-Irritating Iron Complex: Supplies elemental iron bound in a stable complex that passes through the stomach without causing significant gastric irritation. It is actively absorbed across duodenal enterocytes, minimizing localized gastrointestinal distress, dark staining, and constipation.
• Hemoglobin Incorporation: Incorporated directly into the protoporphyrin ring of heme within erythroblasts, driving functional hemoglobin synthesis to restore oxygen-carrying capacity across peripheral blood tissues.
• DNA Synthesis & Cell Maturation (Folic Acid & B12): Folic Acid and Vitamin $\text{B}_{12}$ act as essential coenzymes in purine and thymidylate synthesis, preventing megaloblastic erythrocyte maturation arrest and supporting healthy red blood cell production.

Clinical Indications & Uses

• Up 2 Hema Oral Liquid 10ml 10s is indicated for:
• Treatment and prevention of iron deficiency anemia (IDA) and associated nutritional deficiencies in adults and adolescents
• Prophylactic hematinic fortification during pregnancy, lactation, and post-surgical or postpartum recovery
• Replenishing depleted systemic iron stores resulting from heavy menstrual bleeding, chronic occult blood loss, or restricted vegetarian diets

Usage Guidance & Safety Precautions

Administration:

• Drink 1 single-dose liquid vial ($10\text{ml}$) directly or mix with a small amount of water or fruit juice. Take during or immediately after a main meal to maximize gastrointestinal tolerance. Shake the vial well before use.

Recommended Dosage:

• Adults and Pregnant Women: Take 1 to 2 vials ($10\text{ml}$ to $20\text{ml}$) daily, or as strictly prescribed by a healthcare provider based on serum ferritin and hemoglobin monitoring.

Precautions & Warnings:

• For oral administration only. STRICTLY NOT FOR INJECTION. Contraindicated in patients with iron overload disorders (hemochromatosis, hemosiderosis), active peptic ulcer disease, or non-iron deficiency anemias (e.g., thalassemia, hemolytic anemia). May cause harmless dark-colored stools. Store below $25^\circ\text{C}$ in a cool, dry place protected from light and direct heat. Keep out of reach of children.