VITAMIN B12 1000MCG CAPS 90S (CYNOCOBALAMINE)

Overview & Mechanism of Action

• Vitamin B12 1000mcg Capsules ($90\text{-capsule}$ bottle of high-potency oral Cyanocobalamin) provides essential coenzyme support for DNA synthesis, erythropoiesis, and nervous system integrity:
• Erythropoiesis & DNA Synthesis: Serves as a vital cofactor for methionine synthase, facilitating the conversion of homocysteine to methionine and regenerating active tetrahydrofolate required for normoblastic erythrocyte maturation and nucleic acid synthesis.
• Myelin Sheath & Neurological Function: Functions as a precursor for methylmalonyl-CoA mutase, supporting fatty acid synthesis integral to the structural maintenance of the myelin sheath surrounding peripheral nerves and spinal cords.
• Homocysteine Regulation & Energy Metabolism: Aids in lowering elevated plasma homocysteine levels—a key biomarker for cardiovascular risk—while driving mitochondrial energy conversion to combat physical fatigue and lethargy.

Clinical Indications & Uses

• Vitamin B12 1000mcg Capsules 90s is indicated for:
• Prevention and management of Vitamin $\text{B}_{12}$ deficiency anemia (megaloblastic and pernicious anemia)
• Nutritional supplementation for vegans, strict vegetarians, elderly individuals, and patients with impaired gastrointestinal absorption (e.g., post-bariatric surgery, chronic gastritis)
• Peripheral nerve support in individuals experiencing numbness, tingling, or peripheral neuropathy associated with subclinical cobalamin deficiency

Usage Guidance & Safety Precautions

Administration:

• Swallow 1 capsule daily with food or immediately after a meal along with a full glass of water. Take consistently at the same time each day for optimal cellular uptake.

Recommended Dosage:

• Adults: Take 1 capsule ($1000\mu\text{g}$) daily, or as directed by a healthcare professional.

Precautions & Warnings:

• For oral administration only. Do not exceed the recommended daily dose unless prescribed by a physician. Use with caution in patients with Leber's hereditary optic neuropathy, as cyanocobalamin may accelerate optic atrophy. Large doses may interact with medications like chloramphenicol, metformin, proton pump inhibitors, and H2-receptor antagonists. Store below $25^\circ\text{C}$ in a cool, dry place away from direct heat and light. Keep out of reach of children.