YUCRAN D 5G SATCHETS 6S

Overview & Mechanism of Action

• Yucran D 5g Sachets ($6\text{-sachet}$ box containing a water-soluble oral powder formulated with D-Mannose and Proanthocyanidins) provides targeted dual-action bacterial inhibition across the lower urinary tract:
• Anti-Adhesion & Anti-Infective Action (D-Mannose & Cranberry PACs): D-Mannose competitively binds to Type 1 fimbriae of uropathogenic Escherichia coli (E. coli), while Cranberry Proanthocyanidins (PACs) neutralize P-fimbriae. This dual blockade prevents bacteria from anchoring to the urothelial lining, allowing them to be naturally flushed out during micturition.
• Bladder Wall Protection & Cystitis Relief: Reduces microbial load and prevents bacterial biofilm formation along the mucosal lining of the bladder without disrupting normal intestinal flora or inducing antibiotic resistance.
• Urothelial Defense Enhancement: Helps calm local inflammation, reduce tissue hyper-reactivity, and soothe symptoms of dysuria, frequency, and bladder discomfort.

Clinical Indications & Uses

• Yucran D 5g Sachets 6s is indicated for:
• Prophylaxis and supportive management of acute and recurrent Urinary Tract Infections ($\text{UTIs}$) and cystitis
• Prevention of post-coital or catheter-associated bacterial colonization in the urinary tract
• Relief of urinary burning, frequency, and irritation caused by lower urinary tract bacterial contamination

Usage Guidance & Safety Precautions

Administration:

• Dissolve the contents of 1 sachet ($5\text{g}$) thoroughly in a glass of water ($150\text{ml}$ to $200\text{ml}$) and consume immediately. Increase overall daily fluid intake to facilitate optimal urinary flushing.

Recommended Dosage:

• Adults and Adolescents: Take 1 sachet daily for routine prevention, or 1 sachet twice daily during acute UTI flare-ups as an adjunct to prescribed therapy, or as directed by a healthcare professional.

Precautions & Warnings:

• For oral administration only. Use with caution in patients with a history of nephrolithiasis (kidney stones), as high cranberry intake may elevate urinary oxalate levels. Diabetics should account for carbohydrate/excipient content in each sachet. Consult a doctor before use during pregnancy or breastfeeding. Store below $25^\circ\text{C}$ in a cool, dry place protected from direct heat and moisture. Keep out of reach of children.