OSAM D 830MG/400IU TABS 30S

Overview & Mechanism of Action

• Osam D Tablets (30-tablet pack containing Calcium Carbonate $830\text{mg}$ and Colecalciferol / Vitamin D3 $400\text{IU}$) provides essential structural elements and transport cofactors for skeletal maintenance:
• Skeletal Mineral Matrix Support (Calcium Carbonate $830\text{mg}$): Delivers bioavailable ionized calcium ($\text{Ca}^{2+}$) required for hydroxyapatite crystal formation within the extracellular bone matrix, counteracting parathyroid hormone ($\text{PTH}$)-induced bone resorption.
• Intestinal Mineral Absorption (Vitamin D3 / Colecalciferol $400\text{IU}$): Facilitates active transport of calcium across the intestinal mucosal brush border into systemic blood circulation by upregulating calbindin transport proteins.
• Bone Density Maintenance: Synergistically improves total bone mineral density (BMD), helping prevent structural fragility and slowing progressive skeletal degradation in aging populations.

Clinical Indications & Uses

• Osam D 830mg/400IU Tablets 30s is indicated for:
• Prevention and treatment of calcium and vitamin D deficiencies in adults and high-risk populations
• Adjunctive nutritional support alongside antiresorptive therapy in osteoporosis management
• Supporting skeletal strength during periods of increased calcium demands or age-related mineral loss

Usage Guidance & Safety Precautions

Administration:

• Swallow tablets with a glass of water, or chew thoroughly if using chewable variants, preferably after meals.

Recommended Dosage:

• Adults and Elderly: Take 1 to 2 tablets daily, or as advised by a healthcare provider.

Precautions & Warnings:

• For oral administration. Contraindicated in hypercalcemia, hypercalciuria, severe renal impairment, nephrolithiasis (kidney stones), or hypervitaminosis D. Monitor serum and urinary calcium levels during long-term therapy in renal insufficiency. Separate administration times by at least 2 to 3 hours when taking concomitant bisphosphonates, tetracyclines, or iron supplements. Store below $25^\circ\text{C}$ in a dry place. Keep out of reach of children.