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RINACET (CETRIZINE)10MG TABS 100S

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Pack: Box 100

Rinacet (Cetirizine) 10mg Tablets 100s is a fast-acting, 24-hour second-generation antihistamine formulated to provide comprehensive relief from sneezing, runny nose, itchy or watery eyes, and allergic skin conditions like hives without causing marked drowsiness.

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Overview & Mechanism of Action

  • Rinacet Tablets (bulk pack of 100 tablets containing 10mg Cetirizine Hydrochloride) delivers long-lasting, selective peripheral antihistaminic protection against common environmental and contact allergens:
  • Selective Peripheral $\text{H}_1$-Receptor Antagonism (Cetirizine HCl): Potently and competitively blocks peripheral $\text{H}_1$-histamine receptors, preventing histamine from binding to vascular and mucosal cells. This blunts allergic cascades, stopping vasodilation, capilary permeability, and mucosal swelling.
  • Inhibition of Inflammatory Mediator Release: Suppresses the late-phase recruitment of eosinophils to dermal and respiratory tissues, reducing the late-stage tissue inflammation associated with chronic allergic exposure.
  • Minimal Central Nervous System Penetration: Has low lipophilicity and high selectivity for peripheral receptors, minimizing blood-brain barrier crossing to provide effective relief with significantly lower sedation risks compared to first-generation antihistamines.

Clinical Indications

  • Rinacet (Cetirizine) 10mg Tablets 100s is indicated for:
  • Symptomatic relief of seasonal allergic rhinitis (hay fever) and perennial allergic rhinitis (nasal congestion, sneezing, rhinorrhea, nasal itching)
  • Management of ocular allergic symptoms including itching, lacrimation, and redness (allergic conjunctivitis)
  • Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria, relieving severe itching, hives, and wheals

Usage Guidance & Safety Precautions

Administration:

  • Swallow tablet whole with a glass of water. Can be taken with or without food.

Recommended Dosage:

  • Adults and Children over 12 years: Take 1 tablet (10mg) once daily.
  • Children 6–12 years: Take half a tablet (5mg) twice daily or 1 tablet (10mg) once daily.
  • Renal Impairment: Dosage adjustment (e.g., 5mg daily) is recommended in patients with moderate-to-severe renal insufficiency.

Precautions & Warnings:

  • For oral administration only. While classified as non-sedating, mild somnolence may occur in sensitive individuals; exercise caution when driving or operating heavy machinery. Avoid concurrent consumption of alcohol or central nervous system depressants. Consult a physician before use if pregnant, breastfeeding, or managing severe renal or hepatic dysfunction. Store below $25^\circ\text{C}$ in a cool, dry place away from direct light. Keep out of reach of children.