VITAMIN K+D 120MCG/1000IU S/GEL 60S(MK-7 FROM NATTO BEAN)

Overview & Mechanism of Action

• Vitamin K+D Softgels ($60\text{-softgel}$ bottle providing $1000\text{ IU}$ Vitamin D3 alongside $120\mu\text{g}$ Vitamin K2 as Menaquinone-7 from fermented Natto beans) provides micro-nutritional synergy for skeletal and cardiovascular preservation:
• Calcium Absorption & Bone Mineralization ($\text{Vitamin D}_3$): Cholecalciferol ($\text{Vitamin D}_3$) enhances intestinal absorption of calcium and phosphorus, elevating circulating blood calcium levels and stimulating osteoblast-mediated bone matrix formation.
• Arterial Carboxylation & Bone Targeting ($\text{Vitamin K}_2\text{ MK-7}$): Menaquinone-7 ($\text{MK-7}$) acts as an essential cofactor for $\gamma$-glutamyl carboxylase, activating osteocalcin to bind calcium into bone hydroxyapatite while carboxylating Matrix Gla Protein ($\text{MGP}$) to prevent soft tissue calcification in blood vessels and arterial walls.
• High Bioavailability Natto Extract: Sourced from fermented soybean Natto, the all-trans $\text{MK-7}$ isomer provides extended biological half-life and superior systemic bioavailability compared to synthetic forms or short-chain Menaquinone-4 ($\text{MK-4}$).

Clinical Indications & Uses

• Vitamin K+D 120mcg/1000IU Softgels 60s is indicated for:
• Daily dietary supplementation to support optimal bone mineral density, joint structure, and skeletal strength in adults and seniors
• Cardiovascular support to promote arterial flexibility and prevent unwanted vascular calcium deposition
• Adjunctive nutritional management in individuals with subclinical Vitamin D deficiency, low sun exposure, or elevated risk of osteopenia

Usage Guidance & Safety Precautions

Administration:

• Take 1 softgel daily with a fat-containing meal (such as breakfast or lunch) along with a full glass of water. Consuming with dietary fat enhances fat-soluble vitamin absorption.

Recommended Dosage:

• Adults: Take 1 softgel daily, or as recommended by a qualified physician or nutritionist.

Precautions & Warnings:

• For oral administration only. Contraindicated or requires mandatory medical supervision in patients taking oral vitamin K antagonists/anticoagulants (e.g., Warfarin, Coumadin), as Vitamin K2 directly opposes anticoagulant activity. Patients with hypercalcemia, hypervitaminosis D, or severe renal impairment should consult their physician before use. Contains soy derivatives (Natto bean extract); exercise caution in individuals with severe soy allergies. Store below $25^\circ\text{C}$ in a cool, dry place protected from heat and moisture. Keep out of reach of children.