VITAMIN K2 MK7 TABS 30S (HN)

Overview & Mechanism of Action

• Vitamin K2 MK7 Tablets ($30\text{-tablet}$ pack containing highly bioavailable Menaquinone-7) serves as an essential cofactor for carboxylating vitamin K-dependent proteins involved in systemic calcium management:
• Targeted Bone Matrix Mineralization (Osteocalcin Activation): Acts as an obligate cofactor for the enzyme $\gamma$-glutamyl carboxylase, which converts inactive uncarboxylated osteocalcin into active carboxylated osteocalcin in bone tissue. Active osteocalcin binds ionic calcium ($\text{Ca}^{2+}$) and incorporates it into the hydroxyapatite crystalline bone matrix.
• Vascular Anti-Calcification (Matrix Gla Protein Carboxylation): Simultaneously carboxylates Matrix Gla Protein ($\text{MGP}$) produced by vascular smooth muscle cells. Active $\text{MGP}$ is the most potent inhibitor of soft tissue and arterial wall calcification, preventing calcium deposition in arterial walls and preserving vascular elasticity.
• Extended Biological Half-Life & Superior Bioavailability: Compared to short-chain Vitamin K1 or synthetic MK-4, natural Menaquinone-7 ($\text{MK-7}$) exhibits a significantly longer plasma half-life (roughly 72 hours vs. 1–2 hours for K1), ensuring stable systemic serum levels and continuous tissue distribution with once-daily dosing.

Clinical Indications & Uses

• Vitamin K2 MK7 Tablets 30s (HN) is indicated for:
• Prophylaxis and supportive care for age-related bone loss, osteopenia, and osteoporosis
• Prevention of vascular calcification and maintenance of arterial elasticity in cardiovascular wellness regimens
• Complementary nutritional therapy during high-dose Calcium and Vitamin D3 supplementation to ensure safe calcium routing

Usage Guidance & Safety Precautions

Administration:

• Swallow 1 tablet daily with water, preferably during a main meal containing healthy fats to enhance intestinal lipid absorption.

Recommended Dosage:

• Adults: Take 1 tablet daily, or as recommended by a qualified healthcare professional.

Precautions & Warnings:

• For oral dietary consumption only. Contraindicated in patients taking oral Vitamin K antagonist anticoagulants (such as Warfarin / Coumadin), as Vitamin K2 directly neutralizes the blood-thinning mechanism of coumarins. Patients with hypercalcemia or known bleeding disorders should consult a physician prior to use. Store below $25^\circ\text{C}$ in a cool, dry place away from heat and direct sunlight. Keep out of reach of children.