ACNEVATE GEL 30G

Overview & Mechanism of Action

• Acnevate Gel (30g) is a targeted dermatological topical gel specifically formulated for the treatment and ongoing management of mild-to-moderate acne vulgaris. It operates through complementary therapeutic pathways to treat active breakouts and prevent future lesions:
• Targeted Antibacterial Action (Clindamycin Phosphate): Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of Cutibacterium acnes (Propionibacterium acnes), significantly reducing bacterial colonization within hair follicles and sebaceous glands.
• Anti-Inflammatory & Sebum-Control Action (Nicotinamide / Niacinamide): Inhibits pro-inflammatory cytokines, reducing cutaneous redness, swelling, and localized tissue irritation. Additionally, it helps regulate sebum production and prevents post-inflammatory hyperpigmentation.
• Non-Comedogenic Penetration: The lightweight, water-based gel vehicle penetrates deeply into clogged pores without leaving an oily residue or exacerbating comedone formation.

Clinical Indications

• Acnevate Gel 30g is indicated for:
• Treatment of mild to moderate inflammatory acne vulgaris (papules, pustules, and inflamed spots)
• Clearing blocked pores and preventing the formation of new acne comedones
• Reducing post-acne inflammatory redness, hyperpigmentation, and skin blemishes
• Soothing cutaneous inflammation and balancing sebum production in acne-prone skin

Usage Guidance & Safety Precautions

• Administration: Wash the affected skin area thoroughly with a mild cleanser and pat dry gently. Apply a thin layer of Acnevate Gel to clean, dry skin covering the entire affected area 1 to 2 times daily (morning and evening), or as directed by a dermatologist.

Recommended Dosage: Apply sparingly. Wash hands thoroughly before and after application.

Precautions & Warnings: For external dermatological use only; avoid contact with eyes, lips, mouth, nostrils, and broken skin. May cause mild local skin irritation, dryness, peeling, or a mild burning sensation upon initial use. Use a gentle non-comedogenic moisturizer and daily broad-spectrum sunscreen during treatment. Discontinue use if severe skin irritation or allergic contact dermatitis occurs.