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ALATROL SYRUP 60ML

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Alatrol Syrup 60ml is a fast-acting, non-drowsy antihistamine syrup containing Cetirizine Hydrochloride (5mg/5ml) to rapidly relieve sneezing, runny nose, itchy eyes, and allergic skin conditions in adults and pediatric patients.

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Overview & Mechanism of Action

  • Alatrol Syrup (60ml bottle) is a second-generation $H_1$-receptor antagonist engineered for effective, long-acting relief from peripheral allergic manifestations:
  • Selective Peripheral $H_1$-Receptor Antagonism (Cetirizine HCl): Selectively binds to and blocks peripheral $H_1$ histamine receptors on mucosal vascular endothelial cells, smooth muscle, and peripheral cutaneous nerves. By preventing endogenous histamine binding, it halts the immediate allergic cascade.
  • Suppression of Inflammatory Mediator Migration: Suppresses the late-phase recruitment and activation of eosinophils and other inflammatory cells at reaction sites, significantly reducing tissue swelling, nasal congestion, and skin redness.
  • Minimal Central Sedation: Poorly crosses the blood-brain barrier compared to first-generation antihistamines, delivering targeted antiallergic action with a minimal incidence of central nervous system sedation or drowsiness.

Clinical Indications

  • Alatrol Syrup 60ml is indicated for:
  • Rapid relief of nasal and ocular symptoms of seasonal allergic rhinitis (hay fever) and perennial allergic rhinitis
  • Symptomatic treatment of chronic idiopathic urticaria (hives), relieving localized skin itching, wheals, and redness
  • Management of allergic skin disorders, prickly heat, and allergic conjunctivitis

Usage Guidance & Safety Precautions

Administration:

  • Measure the dose accurately using a medicinal measuring cup or syringe. May be taken with or without food.

Recommended Dosage:

  • Adults & Children over 12 years: 10ml (10mg) once daily.
  • Children 6 to 12 years: 5ml (5mg) twice daily or 10ml (10mg) once daily.
  • Children 2 to 6 years: 2.5ml (2.5mg) twice daily or 5ml (5mg) once daily.
  • Children under 2 years: Use strictly under direct pediatric supervision.

Precautions & Warnings:

  • Although non-sedating for most individuals, exercise caution when driving or operating machinery until individual response is established. Avoid concurrent consumption of alcohol or central nervous system depressants. Adjust dose in patients with moderate to severe renal impairment. Store below 30°C in a dry place protected from direct light. Keep out of reach of children.