CHLORPHENIRAMINE EXPECTORANT (PIRINOX) 100ML

Overview & Mechanism of Action

• Chlorpheniramine Expectorant (Pirinox) 100ml is a liquid oral combination formulation engineered to facilitate mucus clearance and relieve bronchial discomfort associated with upper respiratory tract infections and allergic coughs. Its active therapeutic actions include:
• Chlorpheniramine Maleate (2.5 mg / 5 ml): A potent first-generation H1-receptor antihistamine that competitively blocks histamine receptors on bronchial and vascular smooth muscle. This prevents allergic reactions, reduces mucosal swelling, and stops persistent runny nose, sneezing, and throat irritation.
• Ammonium Chloride (125 mg / 5 ml): Functions as a reflex expectorant. It irritates the gastric mucosa, reflexively stimulating bronchial secretory glands to increase fluid secretions, thereby thinning dense phlegm and aiding its expulsion via ciliary motion.
• Sodium Citrate (55 mg / 5 ml) & Menthol: Acts as a mucolytic liquefying agent that liquefies tenacious mucous plugs in the respiratory tract while providing a soothing, cooling effect on inflamed pharyngeal tissues.
• Clinical Indications
• Chlorpheniramine Expectorant (Pirinox) 100ml is indicated for:
• Symptomatic relief of productive (wet) coughs accompanied by sticky, thick bronchial secretions
• Easing chest tightness and mucus accumulation in acute bronchitis, tracheobronchitis, and the common cold
• Managing cough fits triggered by seasonal allergic rhinitis, post-nasal drip, and throat tickle
• Promoting airway clearance during viral upper respiratory tract infections
• Usage Guidance & Safety Precautions
• Administration: Shake the bottle well before use. Measure carefully using a calibrated measuring spoon or dosing cup.
• Recommended Dosage:
• Adults & Children (over 12 years): 5 ml to 10 ml taken every 4 to 6 hours (up to a maximum of 4 doses in 24 hours).
• Children (6–12 years): 2.5 ml to 5 ml taken every 4 to 6 hours.
• Children under 6 years: Not recommended unless under direct supervision of a healthcare provider.
• Precautions & Warnings: Chlorpheniramine causes drowsiness, sedation, and psychomotor impairment. Do not drive, operate heavy machinery, or consume alcohol while taking this medication. Use with caution in patients with glaucoma, asthma, urinary retention, severe cardiovascular disease, or hepatic impairment.