PHILCOLIN DM COUGH SYR 60ML

Overview & Mechanism of Action

• Philcolin DM Cough Syrup (60ml bottle) is a multi-action respiratory formulation designed specifically to suppress non-productive, dry, irritating coughs and relieve accompanying allergic nasal symptoms:
• Central Cough Reflex Suppression (Dextromethorphan HBr): Acts centrally on the medullary cough center in the brainstem to elevate the cough threshold. It effectively silences non-productive, tickly cough spasms without suppressing respiratory drive or impairing mucociliary clearance.
• Histamine Blockade & Anti-Allergic Relief (Chlorpheniramine Maleate): Competitively antagonizes peripheral $\text{H}_1$-histamine receptors, inhibiting histamine-mediated mucosal swelling, tickling throat irritation, watery eyes, sneezing, and post-nasal drip that trigger cough reflexes.
• Nasal Decongestion (Phenylephrine HCl / Sympathomimetic Action): Induces vasoconstriction of dilated arterioles in the nasal mucosa, reducing tissue swelling, relieving sinus pressure, and unblocking congested upper airways.

Clinical Indications

• Philcolin DM Cough Syrup 60ml is indicated for:
• Rapid suppression of dry, hacking, non-productive coughs associated with upper respiratory tract infections, cold, or flu
• Relief of tickly throat irritation, allergic cough, and cough caused by post-nasal drip
• Symptomatic relief of accompanying allergic symptoms such as sneezing, runny nose, and watery eyes
• Easing nasal and sinus congestion associated with allergic rhinitis or acute coryza

Usage Guidance & Safety Precautions

Administration:

• Measure the dose accurately using a calibrated measuring cup or spoon. May be taken with or without food.

Recommended Dosage:

• Adults & Children over 12 years: 10ml (2 teaspoonfuls) every 6 to 8 hours as needed. Maximum 40ml in 24 hours.
• Children 6 to 12 years: 5ml (1 teaspoonful) every 6 to 8 hours as needed under adult supervision. Maximum 20ml in 24 hours.
• Children under 6 years: Not recommended unless prescribed by a paediatrician.

Precautions & Warnings:

• Contraindicated with Monoamine Oxidase Inhibitors (MAOIs): Do not take concurrently with or within 14 days of stopping an MAOI antidepressant, as severe hyperpyrexia or hypertensive crisis may occur. May cause mild drowsiness or dizziness; exercise caution when driving or operating machinery. Avoid alcohol during treatment. Use with caution in patients with hypertension, hyperthyroidism, glaucoma, or cardiovascular disease.